HEMATOLOGY:-leucocytes-WBC

 WBC:-

-nucleated cells ,without hemoglobin -colorless

-irregular shape

-lifespan-hour, days

-normal count 4000-11000/cellmm/mm3

Leucocytes -condition in which there is an increase in WBC COUNT -mature can be controlled

-leukemia -increase in WBC ,immature -uncontrollable -non functioning

-leukocytopenia-deacrease IN WBC count ,due to exposure to XRAYS, depression of bone marrow ,too much use of antibiotics-effects the bone ,marrow

Classification:-

1)agranlocytes(depend on agranule and unlobed nucleus)

i)lymphocytes

ii)monocyte

2)granulocyte

(lobed nuclease granules are present)

i)neutrophil

ii)esinophil

iii)basophil

neutrophil	eosinophil	basophil	lymphocyte
60-70%	2-4%	0-1%	25-30%
Cellsize:-10-14 micron	10-14 micron0	10-12 micron	Small-7-8 m Large -10-14 m
Defence:-first line	Release of histamine	It releases -heparin	Provide immunity
Nuclease -multilobed 2-5 nuclease	One 2 lobe	No lobe	Singleunlobed
Cytoplasm-fine granules	Coarse granulues	Coarse granules	Clear cytoplasm
Staining -both acidic and basic	Acidic staining	Basic stain

monocyte

3-8%

18-20 m

phagocytosis

Horseshoe shaped

Less cytoplasm

Neutrophil classified according to no. of lobes

1. 2 -lobed

2. 2)3 lobed-40-45%

3. 4 lobed 15-20%

4. 5 lobed -minimun 4-10%

Function of WBC :_

Whenever there is an injury or any microbial infection the neutrophils runs to the affected part 

-eosinophil release histamine during allergic reaction

-basophil releases heparin the natural anti coagulant to provide fluid property of blood